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GRIN2B 抗体 (C-Term)

This anti-GRIN2B antibody is a 兔 多克隆 antibody detecting GRIN2B in WB, IHC, ELISA 和 IP. Suitable for 大鼠. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN361395
发货至: 中国

Quick Overview for GRIN2B 抗体 (C-Term) (ABIN361395)

抗原

See all GRIN2B 抗体
GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This GRIN2B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
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    C-Term

    特异性

    Specific for endogenous levels of the ~180 kDa NR2B subunit of the NMDA receptor. Immunolabeling is blocked by preadsorption of antibody with the fusion protein used to generate the antibody. No reactivity towards the NR2A and NR2C subunits.

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Our NMDA NR2B Subunit rabbit polyclonal primary antibody is produced in-house. It detects NMDA NR2B Subunit and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC, IP.

    纯化方法

    Prepared from pooled rabbit serum by affinity purification using a column to which the fusion protein immunogen was coupled.

    免疫原

    Fusion protein from the C-terminal region of the NR2B subunit of the rat NMDA receptor.

    亚型

    IgG
  • 应用备注

    Dilution Range: IP: 3 μL per 200 μg lysate

    Dilution Range: WB Brain: 1:1000

    Dilution Range: WB: 1:1000

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Reconstitute in 50 μl phosphate buffered saline (PBS: 137 mM NaCl, 7.5 mM Na2HPO4, 2.7 mM KCl, 1.5 mM KH2PO4, pH 7.4) before use. After reconstitution it is recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

    有效期

    12 months
  • Brady, Diaz, Iuso, Everett, Valenzuela, Caldwell: "Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 3, pp. 1062-7, (2013) (PubMed).

    Hicklin, Wu, Radcliffe, Freund, Goebel-Goody, Correa, Proctor, Lombroso, Browning: "Alcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 16, pp. 6650-5, (2011) (PubMed).

    Kurup, Zhang, Xu, Venkitaramani, Haroutunian, Greengard, Nairn, Lombroso: "Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 17, pp. 5948-57, (2010) (PubMed).

  • 抗原

    GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

    别名

    GRIN2B

    背景

    Synonyms: AW490526 antibody, EIEE27 antibody, Glutamate [NMDA] receptor subunit epsilon 2 antibody, Glutamate [NMDA] receptor subunit epsilon-2 antibody, Glutamate Receptor Ionotropic N Methyl D Aspartate 2B antibody, Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B antibody, Glutamate receptor ionotropic NMDA2B antibody, Glutamate receptor subunit epsilon 2 antibody, Glutamate receptor ionotropic NMDA2B (epsilon 2) antibody, GRIN 2B antibody, GRIN2B antibody, hNR 3 antibody, hNR3 antibody, MGC142178 antibody, MGC142180 antibody, MRD6 antibody, N methyl D asparate receptor channel subunit epsilon 2 antibody, N methyl D aspartate receptor subtype 2B antibody, N methyl D aspartate receptor subunit 2B antibody, N methyl D aspartate receptor subunit 3 antibody, N-methyl D-aspartate receptor subtype 2B antibody, N-methyl-D-aspartate receptor subunit 3 antibody, NMDA NR2B antibody, NMDA R2B antibody, NMDAR2B antibody, NMDE2 antibody, NMDE2_HUMAN antibody, NME2 antibody, NR2B antibody, NR3 antibody

    Description Logic: Our NMDA NR2B Subunit rabbit polyclonal primary antibody is produced . It detects NMDA NR2B Subunit and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC, IP.

    Gene Name Alternatives: GRIN2B

    分子量

    180 kDa

    基因ID

    24410

    UniProt

    Q00960

    途径

    Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
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