Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
限制
仅限研究用
状态
Liquid
缓冲液
100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
储存条件
-20 °C
抗原
DLG4
(Discs, Large Homolog 4 (Drosophila) (DLG4))
别名
DLG4
背景
PSD-95 is a very prominent component of the postsynaptic densities of synapses. It contains three PDZ domains which play key roles in its interactions with other proteins in the synapse. It has been proposed that these PDZ domains organize glutamate receptors and their associated signaling proteins and determine the size and strength of synapses (Kim and Sheng, 2004). Recent work suggests that interaction of the NMDAR with PSD-95 via these PDZ domains can be regulated by phosphorylation (Chung et al., 2004). Anti-PSD-95 Western blot of rat hippocampal (Hipp) lysate showing specific immunolabeling of the ~95k PSD-95 protein.