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- 抗原 See all TUBB3 抗体
- TUBB3 (Tubulin, beta 3 (TUBB3))
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TUBB3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- Specific for the ~55kDa beta III tubulin protein. This clone is similar to the monoclonal antibody Tuj1. It is expected that this antibody will have wide species cross reactivity.
- 交叉反应
- 大鼠
- 纯化方法
- Protein G purified culture supernatant
- 免疫原
- Synthetic peptide corresponding to amino acid residues specific to beta III tubulin conjugated to KLH
- 克隆位点
- AA10
- 亚型
- IgG
- Top Product
- Discover our top product TUBB3 Primary Antibody
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- 应用备注
- Recommended Dilution: WB: 1:10,000 IHC: 1:1,000 Quality Control: Western blots performed on each lot.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
- 储存条件
- -20 °C
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- 抗原
- TUBB3 (Tubulin, beta 3 (TUBB3))
- 别名
- TUBB3 (TUBB3 产品)
- 别名
- CDCBM antibody, CFEOM3A antibody, TUBB4 antibody, beta-4 antibody, TUBB3 antibody, 3200002H15Rik antibody, M(beta)3 antibody, M(beta)6 antibody, tubb3 antibody, tubulin beta 3 class III antibody, tubulin, beta 3 class III antibody, tubulin beta 3 class III L homeolog antibody, beta-tubulin 3 antibody, tubulin beta-3 chain antibody, beta tubulin 3 antibody, TUBB3 antibody, Tubb3 antibody, tubb3 antibody, tubb3.L antibody, LOC100581245 antibody, tub3 antibody
- 背景
- Tubulin is the major constituent of microtubules, existing as a heterodimer of the alpha and beta subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins (Lee et al., 1990). Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy (Katsetos et al., 2003) Anti-Beta III Tubulin Western blot of rat cortex lysate showing specific immunolabeling of the ~55k beta III tubulin protein.
- 分子量
- '55 kDa
- 基因ID
- 246118
- UniProt
- Q4QRB4
- 途径
- Microtubule Dynamics, M Phase
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