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NEFM 抗体 (C-Term)

This anti-NEFM antibody is a 小鸡 多克隆 antibody detecting NEFM in WB 和 IF. Suitable for 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN361355
发货至: 中国

Quick Overview for NEFM 抗体 (C-Term) (ABIN361355)

抗原

See all NEFM 抗体
NEFM (Neurofilament Triplet M Protein (NEFM))

适用

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大鼠

宿主

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  • 1
小鸡

克隆类型

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  • 34
多克隆

标记

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This NEFM antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    C-Term

    特异性

    Specific for the ~145k Neurofilament M protein.

    交叉反应

    小鸡, 牛, 人, 小鼠, 大鼠

    纯化方法

    Total IgY fraction

    免疫原

    Preparation containing the extreme C-terminus expressed in and purified from E. Coli
  • 应用备注

    Recommended Dilution: WB: 1:5,000 IF: 1:1000 Quality Control: Western blots performed on each lot.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    total IgY fraction in PBS + 10 mM Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Glass, Kelm-Nelson, Szot, Lake, Connor, Ciucci: "Functional characterization of extrinsic tongue muscles in the Pink1-/- rat model of Parkinson disease." in: PloS one, Vol. 15, Issue 10, pp. e0240366, (2020) (PubMed).

  • 抗原

    NEFM (Neurofilament Triplet M Protein (NEFM))

    别名

    NEFM

    背景

    Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (2). Anti-Neurofilament M Western blot of rat cortex lysate showing specific immunolableing of the ~ 145k NF-M protein.

    分子量

    '145 kDa

    基因ID

    24588

    UniProt

    P12839

    途径

    Brown Fat Cell Differentiation
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