Thymidine Glycol 抗体
The 小鼠 单克隆 anti-Thymidine Glycol antibody is suitable to detect Thymidine Glycol in samples from 化学剂. It has been validated for IHC.
产品编号 ABIN361277
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for Thymidine Glycol 抗体 (ABIN361277)
抗原
Thymidine Glycol (TG)
适用
化学剂
宿主
小鼠
克隆类型
单克隆
标记
This Thymidine Glycol antibody is un-conjugated
应用范围
Immunohistochemistry (IHC)
克隆位点
2E8
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特异性
- Specific to DNA containing thymidine glycol. Cross reactivity is checked to oxidized dC polymer, oxidized dG polymer and oxidized dA polymer.
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免疫原
- Thymidine glycol polymer
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亚型
- IgG1 kappa
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应用备注
- Tested for IHC. User should determine optimum titer for each application.
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- 100ug/ml
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缓冲液
- 100?g/mL IgG in 10 mM Phosphate buffered saline, pH7.4 containing 1.0 % BSA
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储存条件
- -20 °C
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- Thymidine Glycol (TG)
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物质类
- Chemical
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背景
- Thymidineglycol (TG) is one of the major oxidation products of DNA. Thymidine (T) can be damaged by oxidative stress such as radiation and energy metabolism. Two different pathways to form TG have been suggested. Deoxythymidine in DNA is directly oxidised by hydroxy radical, to form TG. TG can be also formed through an intermediate thymidine chlorohydrin, which is derived from hypochlorous acid (HOCl) from neutrophil myeloperoxidase. Thymidineglycol is derived from DNA, not from RNA. TG is the oxidative stress marker secific for DNA damage.
抗原
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