4-Hydroxy-2-Hexenal (4-HHE) 抗体
Our Local Distributor
北京 101111
Quick Overview for 4-Hydroxy-2-Hexenal (4-HHE) 抗体 (ABIN361275)
抗原
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Specific for HHE-modified protein (especially HHE-His Michael adduct)
-
免疫原
- HHE-modified keyhole-lympet hemocyanine
-
亚型
- IgG1 kappa
-
-
-
-
应用备注
- Immunohistochemistry: It is recommended that the antibody be tried at 0.5-1.0 micro g/mL on paraformaldehyde fixed tissue.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Frozen in 10 mM PBS containing 0.1 % NaN3 and 0.1 % BSA
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
-
-
: "Protein modifications by 4-hydroxynonenal and 4-hydroxyhexenal in light-exposed rat retina." in: Investigative ophthalmology & visual science, Vol. 46, Issue 10, pp. 3859-68, (2005) (PubMed).
: "Protein-bound 4-hydroxy-2-hexenal as a marker of oxidized n-3 polyunsaturated fatty acids." in: Journal of lipid research, Vol. 45, Issue 4, pp. 626-34, (2004) (PubMed).
-
-
- 4-Hydroxy-2-Hexenal (4-HHE)
-
物质类
- Chemical
-
背景
- 4-hydroxy-2-alkenal is one of the major lipid peroxidation products, and shows many biological effects such as high toxicity to cells. Among them, 4-hydroxy-2-hexenal (HHE) is an aldehyde formed during peroxidation of n-3 fatty acids such as docosahexaenoic acid. HHE is highly reactive aldehyde and reacts with histidine residue of protein to form Michael-addition type adducts. This antibody is specific for HHE-histidine Michael adduct (HHE-His) and enable to detect HHE-His in the tissue samples.
抗原
-