3,5-Dibromo-Tyrosine 抗体
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- 抗原
- 3,5-Dibromo-Tyrosine
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
- 特异性
- This antibody can react with dibromotyrosine (DiBrY), N-acetylated dichloro tyrosine (NAcDiClY), diiodo tyrosine (DiIY), N-bromosuccinimide-treated BSA, HOCl-treated BSA and dibromo-tyrosone conjugated BSA (halogene-modified tyrosine at both 3- and 5-position). Cross reactivity to following analogues have been tested: dityrosine-conjugated BSA, peroxynitrite-treated BSA, tyrosine (Y), chrolotyrosine(ClY), 3-3
- 克隆位点
- 3A5
- 亚型
- IgG1 kappa
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anti-3,5-Dibromo-Tyrosine antibody (Alkaline Phosphatase (AP))
IHC, ELISA, WB, IF, ICC 宿主: 小鼠 Monoclonal 6G3 Alkaline Phosphatase (AP)
anti-3,5-Dibromo-Tyrosine antibodyIHC, ELISA, WB, IF, ICC 宿主: 小鼠 Monoclonal 6G3 unconjugated
anti-3,5-Dibromo-Tyrosine antibody (HRP)IHC, ELISA, WB, IF, ICC 宿主: 小鼠 Monoclonal 6G3 HRP
anti-3,5-Dibromo-Tyrosine antibody (APC)IHC, ELISA, WB, IF, ICC 宿主: 小鼠 Monoclonal 6G3 APC
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- 应用备注
- Immunohistochemistry (Recommended concentration: 10ug/mL IgG) [ref.1] and western blotting.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 储存条件
- -20 °C
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- 抗原
- 3,5-Dibromo-Tyrosine
- 物质类
- Amino Acid
- 背景
- Tyrosine is one of the main targets of protein oxidation, and it have been reported form nitrotyrosine, dityrosine and halogenated tyrosines depending on the type of free radicals. For example, hypochlorous acid (HOCl) and hypobromous acid (HOBr) are derived from neutrophil myeloperoxidase (MPO) and eosinophil peroxidase (EPO), and known to form dihalogenated tyrosines such as DiBrY, DiClY and DiIY. It is expected that DiBrY may be a novel biomarker for tissue damage which is related to inflammatory and allergic disorders.
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