3,5-Dibromo-Tyrosine 抗体
The 小鼠 单克隆 anti-3,5-Dibromo-Tyrosine antibody is suitable to detect 3,5-Dibromo-Tyrosine. It has been validated for IHC, ELISA 和 WB.
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产品编号 ABIN361274
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for 3,5-Dibromo-Tyrosine 抗体 (ABIN361274)
抗原
3,5-Dibromo-Tyrosine
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
克隆位点
3A5
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特异性
- This antibody can react with dibromotyrosine (DiBrY), N-acetylated dichloro tyrosine (NAcDiClY), diiodo tyrosine (DiIY), N-bromosuccinimide-treated BSA, HOCl-treated BSA and dibromo-tyrosone conjugated BSA (halogene-modified tyrosine at both 3- and 5-position). Cross reactivity to following analogues have been tested: dityrosine-conjugated BSA, peroxynitrite-treated BSA, tyrosine (Y), chrolotyrosine(ClY), 3-3
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亚型
- IgG1 kappa
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anti-3,5-Dibromo-Tyrosine antibody
IHC, ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
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应用备注
- Immunohistochemistry (Recommended concentration: 10ug/mL IgG) [ref.1] and western blotting.
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限制
- 仅限研究用
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状态
- Lyophilized
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储存条件
- -20 °C
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- 3,5-Dibromo-Tyrosine
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物质类
- Amino Acid
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背景
- Tyrosine is one of the main targets of protein oxidation, and it have been reported form nitrotyrosine, dityrosine and halogenated tyrosines depending on the type of free radicals. For example, hypochlorous acid (HOCl) and hypobromous acid (HOBr) are derived from neutrophil myeloperoxidase (MPO) and eosinophil peroxidase (EPO), and known to form dihalogenated tyrosines such as DiBrY, DiClY and DiIY. It is expected that DiBrY may be a novel biomarker for tissue damage which is related to inflammatory and allergic disorders.
抗原
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