PNPLA3 抗体 (Internal Region)
(4 references)Quick Overview for PNPLA3 抗体 (Internal Region) (ABIN361184)
抗原
See all PNPLA3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- Internal Region
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原理
- Pnpla3 / Adiponutrin (mouse)
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序列
- EHDICPKVKS TN
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特异性
- This antibody is raised against a peptide derived from the Mouse protein sequence and this peptide differs from Human only in position 2.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence EHDICPKVKSTN, from the internal region of the protein sequence according to NP_473429.2.
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亚型
- IgG
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anti-Patatin-Like phospholipase Domain Containing 3 (PNPLA3) (C-Term) antibody
PNPLA3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Patatin-Like phospholipase Domain Containing 3 (PNPLA3) (AA 1-481) antibodyPNPLA3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Patatin-Like phospholipase Domain Containing 3 (PNPLA3) (C-Term) antibodyPNPLA3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Patatin-Like phospholipase Domain Containing 3 (PNPLA3) (AA 377-481) antibodyPNPLA3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Patatin-Like phospholipase Domain Containing 3 (PNPLA3) (C-Term) antibodyPNPLA3 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Patatin-Like phospholipase Domain Containing 3 (PNPLA3) (AA 1-481) antibodyPNPLA3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Immunohistochemistry: Paraffin embedded Human Kidney. Recommended concentration: 8 μg/mL.
Western Blot: Approx 45 kDa band observed in Mouse Adrenal Gland lysates, and also in preliminary testing of Mouse and Human Kidney and Rat Adrenal Gland lysate (calculated MW of 42.6Da according to Mouse NP_473429.2). Recommended concentration: 0.01-0.03
Peptide ELISA: antibody detection limit dilution 1:16000.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Minimize freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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: "Dynamic interactions of ABHD5 with PNPLA3 regulate triacylglycerol metabolism in brown adipocytes." in: Nature metabolism, Vol. 1, Issue 5, pp. 560-569, (2019) (PubMed).
: "Shifts in dietary carbohydrate-lipid exposure regulate expression of the non-alcoholic fatty liver disease-associated gene PNPLA3/adiponutrin in mouse liver and HepG2 human liver cells." in: Metabolism: clinical and experimental, Vol. 63, Issue 10, pp. 1352-62, (2014) (PubMed).
: "Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase. ..." in: Cell metabolism, Vol. 15, Issue 5, pp. 691-702, (2012) (PubMed).
: "Sex-dependent hepatic transcripts and metabolites in the development of glucose intolerance and insulin resistance in Zucker diabetic fatty rats." in: Journal of molecular endocrinology, Vol. 47, Issue 2, pp. 129-43, (2011) (PubMed).
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: "Dynamic interactions of ABHD5 with PNPLA3 regulate triacylglycerol metabolism in brown adipocytes." in: Nature metabolism, Vol. 1, Issue 5, pp. 560-569, (2019) (PubMed).
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- PNPLA3 (Patatin-Like phospholipase Domain Containing 3 (PNPLA3))
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别名
- Pnpla3
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背景
- Pnpla3, patatin-like phospholipase domain containing 3, Adpn, adiponutrin
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分子量
- 42.6kDa
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基因ID
- 80339, 116939, 362972
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NCBI登录号
- NP_473429
抗原
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