XPNPEP1 抗体
Quick Overview for XPNPEP1 抗体 (ABIN360952)
抗原
See all XPNPEP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts to Aminopeptidase P.
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纯化方法
- Protein G chromatography
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免疫原
- BALB/c mice using a membrane protein fraction of isolated rat glomeruli
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亚型
- IgG1
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anti-X-Prolyl Aminopeptidase (Aminopeptidase P) 1, Soluble (XPNPEP1) (C-Term) antibody
Verified XPNPEP1 适用: 人, 小鼠, 大鼠, Pig ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-X-Prolyl Aminopeptidase (Aminopeptidase P) 1, Soluble (XPNPEP1) (AA 2-623) antibodyXPNPEP1 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-X-Prolyl Aminopeptidase (Aminopeptidase P) 1, Soluble (XPNPEP1) (AA 1-623) antibodyXPNPEP1 适用: 人 ELISA, WB, IF, ICC 宿主: 小鼠 Monoclonal AT9C7 unconjugated
anti-X-Prolyl Aminopeptidase (Aminopeptidase P) 1, Soluble (XPNPEP1) (AA 1-623) antibodyXPNPEP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-X-Prolyl Aminopeptidase (Aminopeptidase P) 1, Soluble (XPNPEP1) antibodyXPNPEP1 适用: 人 WB, IHC, IF 宿主: 小鼠 Monoclonal 1E3 unconjugated
anti-X-Prolyl Aminopeptidase (Aminopeptidase P) 1, Soluble (XPNPEP1) antibodyXPNPEP1 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-X-Prolyl Aminopeptidase (Aminopeptidase P) 1, Soluble (XPNPEP1) (AA 44-240) antibodyXPNPEP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry on frozen and paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in sterile water to a concentration of 0.1-1.0 mg/mL. Centrifuge vial prior to opening.
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缓冲液
- PBS pH 6,0
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注意事项
- Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- XPNPEP1 (X-Prolyl Aminopeptidase (Aminopeptidase P) 1, Soluble (XPNPEP1))
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别名
- XPNPEP1
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背景
- Aminopeptidase P (AP-P, X-Pro aminopeptidase) has the unique ability to leave the N-terminal amino acid residue from peptides having proline as the penultimate amino acid residue. Biologically active peptides comprise an important and diverse class of extracellular chemical messengers that mediate a wide range of intercellular interactions. Several bioactive peptides including hormones, neuropeptides, neurotransmitters escape non-specific protease degradation by having an Xaa-Pro motif at their amino termini. Due to its cyclic nature, proline confers resistance to such peptide bonds so that aminopeptidases with broad specificity cannot act upon such peptides. There are a limited number of peptidases that act on peptide bonds involving a proline residue, such as dipeptidyl peptidase II (DPPII) and dipeptidyl peptidase W (DPPIV), and prolidase (which cleaves the Xaa-Pro bond only in dipeptides), or endopeptidases such as prolyl endopeptidase (which cleaves on the carbonyl side of proline residues within a protein or peptide). However, none of these enzymes have been reported to hydrolyze Xaa-Pro bonds located at the N-terminus of peptides and proteins. Therefore, role of AP-P is crucial in this respect. AP-P activity is ubiquitous and has been found in a wide range of organisms including bacteria, yeast and vertebrates. Mammalian AP-Ps exist in membrane-bound and cytosolic forms, which represent two distinct gene products. The cytosolic (soluble) form of aminopeptidase P is found in human leukocytes and rat brain.Synonyms: Aminoacylproline aminopeptidase, Cytosolic aminopeptidase P, Soluble aminopeptidase P, X-Pro aminopeptidase 1, X-prolyl aminopeptidase 1 soluble, XPNPEPL, XPNPEPL1, Xaa-Pro aminopeptidase 1
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基因ID
- 7511
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NCBI登录号
- NP_065116
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UniProt
- Q9NQW7
抗原
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