TWSG1 抗体
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Quick Overview for TWSG1 抗体 (ABIN360945)
抗原
See all TWSG1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody detects Mouse TSG. Other species not tested.
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纯化方法
- Protein A/G Affinity Chromatography
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免疫原
- Purified Mouse Recombinant TSG
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亚型
- IgG2
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anti-Twisted Gastrulation Homolog 1 (TWSG1) (AA 26-223) antibody
TWSG1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Twisted Gastrulation Homolog 1 (TWSG1) (AA 1-223) antibodyTWSG1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F3 unconjugated
anti-Twisted Gastrulation Homolog 1 (TWSG1) (AA 124-223) antibodyTWSG1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6E6 unconjugated
anti-Twisted Gastrulation Homolog 1 (TWSG1) (AA 1-223) antibodyTWSG1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F3 unconjugated
anti-Twisted Gastrulation Homolog 1 (TWSG1) (AA 124-223) antibodyTWSG1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry on frozen sections: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 200 μL sterile PBS and the final concentration is 500 μL/mL.
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缓冲液
- PBS, None
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TWSG1 (Twisted Gastrulation Homolog 1 (TWSG1))
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别名
- TWSG1 / Tsg
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背景
- Twisted gastrulation (TSG) is a secreted, cysteine-rich protein that plays a role in dorsal/ventral patterning in Drosophila and Xenopus by regulating BMP signaling. TSG was originally identified in Drosophila melanogaster and shown to be required for the differentiation of the dorsal amnioserosa cells. Studies of expression and function of Twisted Gastrulation have been performed in Drosophila and Xenopus. Xenopus TSG is expressed in the ventral regions of the embryo during gastrulation, mimicking the BMP-4 expression pattern. TSG is expressed in dorsal cells of the blastoderm embryo, where there are also high levels of activity of Dpp and Screw. Vertebrate TSGs were subsequently cloned in mouse, human, zebrafish and frog. TSG acts as an agonist for BMP signaling by modulating the inhibitory actions of the BMP antagonist, Chordin/Sog, and the cleavage properties of the metalloprotease, xolloid/tolloid. The N-terminal domain of TSG can bind BMP protein directly in vitro and shows BMP antagonist activity.Synonyms: Twisted gastrulation protein homolog 1
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基因ID
- 65960
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NCBI登录号
- NP_075540
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UniProt
- Q9EP52
抗原
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