IL17 Receptor B 抗体 (Extracellular Domain)
Quick Overview for IL17 Receptor B 抗体 (Extracellular Domain) (ABIN360915)
抗原
See all IL17 Receptor B (IL17RB) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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特异性
- This antibody detects Mouse IL-17BR. No cross activity with Mouse IL-17R.
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纯化方法
- Protein A/G Affinity Chromatography
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免疫原
- Recombinant protein of IL-17B R extracellular domain.
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亚型
- IgG2
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应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.
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缓冲液
- PBS without stabilizer
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))
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别名
- IL17RB / IL17BR
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背景
- Recently, a number of cytokines belonging to the interleukin IL17 family have been identified. These are termed as IL17B, IL17C and IL17E. IL17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL17B, C, and E like IL17 are able to induce proinflammatory responses. However, they do not bind to the IL17 receptor suggesting that additional IL17R related receptor might exist. Receptor for IL17B and IL17E have been independently isolated and have been designated as EV127 (in mouse) and IL17RH1 (in human), respectively. IL17E induces activation of NFkB pathway and like IL17 also induces production of IL8. IL17RH1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.Synonyms: Cytokine receptor CRL4, EVI27, IL-17 receptor B, IL-17 receptor homolog 1, IL-17RB, Interleukin-17 receptor B, Interleukin-17B receptor
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基因ID
- 50905
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NCBI登录号
- NP_062529
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UniProt
- Q9JIP3
抗原
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