IL15RA 抗体 (Extracellular Domain)
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Quick Overview for IL15RA 抗体 (Extracellular Domain) (ABIN360913)
抗原
See all IL15RA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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特异性
- This antibody detects IL-15Ralpha. No cross activity to other IGFBPs.
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纯化方法
- Protein A/G affinity chromatography
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免疫原
- Recombinant protein of IL-15Ralpha extracellular domain.
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亚型
- IgG2
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应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IL15RA (Interleukin 15 Receptor, alpha (IL15RA))
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别名
- IL15RA
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背景
- IL15RA is a cytokine receptor that specifically binds IL15 with high affinity. It shares two subunits with the receptor of IL2, the IL2R beta and IL2R gamma chains. This forms the basis of many overlapping biological activities of IL15 and IL2. The IL2 receptor requires an additional IL2-specific alpha subunit for high affinity IL2 binding. This protein is structurally related to IL2R alpha, but is capable of binding IL15 with high affinity independent of other subunits, which suggests the distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. There are nine different isoforms.Synonyms: IL-15R-alpha, IL-15RA, Interleukin-15 receptor subunit alpha
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基因ID
- 16169
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NCBI登录号
- NP_032384
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UniProt
- Q60819
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途径
- JAK/STAT Signaling
抗原
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