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IL1RL1 抗体 (Extracellular Domain)

This anti-IL1RL1 antibody is a 大鼠 单克隆 antibody detecting IL1RL1 in WB. Suitable for 小鼠.
产品编号 ABIN360904
发货至: 中国

Quick Overview for IL1RL1 抗体 (Extracellular Domain) (ABIN360904)

抗原

See all IL1RL1 抗体
IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

适用

  • 61
  • 9
  • 2
  • 2
  • 1
小鼠

宿主

  • 42
  • 15
  • 4
  • 1
  • 1
大鼠

克隆类型

  • 44
  • 19
单克隆

标记

  • 43
  • 6
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL1RL1 antibody is un-conjugated

应用范围

  • 43
  • 23
  • 16
  • 14
  • 6
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

3F22
  • 抗原表位

    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain

    特异性

    This antibody detects IL-1 R4.

    纯化方法

    Protein A/G Affinity Chromatography

    过滤

    0.2 μm filtered

    免疫原

    Purified Mouse Recombinant IL-1 R4 extracellular doamin

    亚型

    IgG2
  • 应用备注

    Western Blot: 1/500 - 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution in PBS

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

    别名

    IL1RL1 / ST2

    背景

    ST2 is a member of the Toll-Interleukin 1 receptor (TIR) superfamily, expressed by mast cells and TH2 helper cells, but not by TH1 effector cells. The majority of TIR superfamily members, which includes the Interleukin-1 receptor (IL-1R1), Toll-like receptors (TLRs) and the cytosolic adaptor proteins MyD88, TIRAP, Trif and TRAM, initiate innate immunity through the ultimate activation of the transcription factor NF-kappaB and are inducers of the inflammatory response. In contrast ST2, which itself is unable to activate NF-kappaB, has been identified as a negative regulator of IL-1R1 and TLR4 signaling by sequestering MyD88 and TIRAP, in line with its role as a crucial receptor in TH2-cell mediated responses.Synonyms: DER4, FIT-1, Homolog of mouse growth stimulation-expressed, Interleukin-1 receptor-like 1, MGC32623

    基因ID

    17082

    NCBI登录号

    NP_001020773

    UniProt

    P14719
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