EDAR 抗体 (Extracellular Domain)
Quick Overview for EDAR 抗体 (Extracellular Domain) (ABIN360882)
抗原
See all EDAR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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特异性
- This antibody detects EDAR and cross reacts with human EDAR.
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纯化方法
- Protein A/G affinity chromatography
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免疫原
- Recombinant extracellular domain of EDAR
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亚型
- IgG2
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应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- EDAR (Ectodysplasin A Receptor (EDAR))
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别名
- EDAR
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背景
- EDAR (Ectodysplasin A receptor) is a receptor for EDA isoform A1, but not for EDA isoform A2. It has a single transmembrane domain, and shows similarity to 2 separate domains of the tumor necrosis factor (TNF) receptor (TNFR) family. It mediates the activation of NF-kappa-B and JNK and may promote caspase independent cell death. Defects in EDAR are a cause of hypohidrotic ectodermal dysplasia.Synonyms: Anhidrotic ectodysplasin receptor 1, DL, Downless homolog, ED1R, ED3, ED5, EDA-A1 receptor, EDA-A1R, EDA1R, EDA3, Ectodermal dysplasia receptor, Ectodysplasin-A receptor, FLJ94390, HRM1, Tumor necrosis factor receptor superfamily member EDAR
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基因ID
- 13608
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NCBI登录号
- NP_034230
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UniProt
- Q9R187
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途径
- Tube Formation, Ubiquitin Proteasome Pathway
抗原
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