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EDAR 抗体 (Extracellular Domain)

The 大鼠 单克隆 anti-EDAR antibody (Clone 9A38) (ABIN360882) specifically detects EDAR in WB. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN360882
发货至: 中国
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Quick Overview for EDAR 抗体 (Extracellular Domain) (ABIN360882)

抗原

See all EDAR 抗体
EDAR (Ectodysplasin A Receptor (EDAR))

适用

  • 42
  • 20
  • 14
  • 8
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 27
  • 17
  • 1
大鼠

克隆类型

  • 26
  • 18
  • 1
单克隆

标记

  • 31
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This EDAR antibody is un-conjugated

应用范围

  • 24
  • 23
  • 9
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)

克隆位点

9A38
  • 抗原表位

    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain

    特异性

    This antibody detects EDAR and cross reacts with human EDAR.

    纯化方法

    Protein A/G affinity chromatography

    免疫原

    Recombinant extracellular domain of EDAR

    亚型

    IgG2
  • 应用备注

    Western Blot: 1/500 - 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    EDAR (Ectodysplasin A Receptor (EDAR))

    别名

    EDAR

    背景

    EDAR (Ectodysplasin A receptor) is a receptor for EDA isoform A1, but not for EDA isoform A2. It has a single transmembrane domain, and shows similarity to 2 separate domains of the tumor necrosis factor (TNF) receptor (TNFR) family. It mediates the activation of NF-kappa-B and JNK and may promote caspase independent cell death. Defects in EDAR are a cause of hypohidrotic ectodermal dysplasia.Synonyms: Anhidrotic ectodysplasin receptor 1, DL, Downless homolog, ED1R, ED3, ED5, EDA-A1 receptor, EDA-A1R, EDA1R, EDA3, Ectodermal dysplasia receptor, Ectodysplasin-A receptor, FLJ94390, HRM1, Tumor necrosis factor receptor superfamily member EDAR

    基因ID

    13608

    NCBI登录号

    NP_034230

    UniProt

    Q9R187

    途径

    Tube Formation, Ubiquitin Proteasome Pathway
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