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PPM1F 抗体 (C-Term)

PPM1F 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN360801
发货至: 中国
  • 抗原 See all PPM1F 抗体
    PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))
    抗原表位
    • 10
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    • 48
    • 2
    • 1
    宿主
    • 42
    • 6
    克隆类型
    • 45
    • 3
    多克隆
    标记
    • 24
    • 5
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPM1F antibody is un-conjugated
    应用范围
    • 33
    • 24
    • 20
    • 11
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to PPM1F.
    纯化方法
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PPM1F.
    亚型
    Ig Fraction
    Top Product
    Discover our top product PPM1F Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western Blot: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))
    别名
    Protein Phosphatase 1F / PPM1F (PPM1F 产品)
    别名
    1110021B16Rik antibody, 4933427B07Rik antibody, CaMKPase antibody, Popx2 antibody, mKIAA0015 antibody, CAMKP antibody, FEM-2 antibody, POPX2 antibody, hFEM-2 antibody, protein phosphatase, Mg2+/Mn2+ dependent 1F antibody, protein phosphatase 1F (PP2C domain containing) antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1F antibody, PPM1F antibody, Ppm1f antibody
    背景
    PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis.Synonyms: Ca(2+)/calmodulin-dependent protein kinase phosphatase, CaM-kinase phosphatase, CaMKPase, KIAA0015, POPX2, Partner of PIX 2, Protein fem-2 homolog
    基因ID
    9647, 9606
    UniProt
    P49593
    途径
    Positive Regulation of Endopeptidase Activity
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