DUSP14 抗体 (C-Term)
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Quick Overview for DUSP14 抗体 (C-Term) (ABIN360795)
抗原
See all DUSP14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to DUSP14.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human DUSP14.
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亚型
- Ig Fraction
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anti-Dual Specificity Phosphatase 14 (DUSP14) (AA 1-198) antibody
DUSP14 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 14 (DUSP14) antibodyDUSP14 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 14 (DUSP14) (AA 1-198) antibodyDUSP14 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4B5-E6 unconjugated
anti-Dual Specificity Phosphatase 14 (DUSP14) (AA 1-198) antibodyDUSP14 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 14 (DUSP14) (AA 1-30), (N-Term) antibodyDUSP14 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB5911 unconjugated
anti-Dual Specificity Phosphatase 14 (DUSP14) (C-Term) antibodyVerified DUSP14 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 14 (DUSP14) antibodyDUSP14 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 14 (DUSP14) (C-Term) antibodyDUSP14 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- DUSP14 (Dual Specificity Phosphatase 14 (DUSP14))
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别名
- DUSP14 / MKP6
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背景
- DUSP14 is involved in the inactivation of MAP kinases. This proein dephosphorylates ERK, JNK and p38 MAP-kinases. In addition to antigen recognition by the T-cell receptor, T-cell activation requires a second signal from a costimulatory receptor, such as CD28, which interacts with B7-1 (CD80) and B7-2 (CD86) ligands on antigen-presenting cells. CD28 costimulation induces transcription of interleukin-2 and stabilizes newly synthesized IL2 through the activation of mitogen-activated protein kinases (MAPKs), such as ERK and JNK, and the subsequent creation of AP1 transcription factor. DUSP14 is a negative regulator of CD28 signaling.Synonyms: Dual specificity protein phosphatase 14, MAP kinase phosphatase 6, MKP-1-like protein tyrosine phosphatase, Mitogen-activated protein kinase phosphatase 6
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基因ID
- 11072, 9606
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UniProt
- O95147
抗原
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