ITPKA 抗体 (C-Term)
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Quick Overview for ITPKA 抗体 (C-Term) (ABIN360691)
抗原
See all ITPKA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 353-382, C-Term
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特异性
- This antibody recognizes Human and Mouse ITPKA at C-term.
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纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- KLH conjugated synthetic peptide between 353~382 amino acids from the C-terminal region of human ITPKA
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亚型
- Ig Fraction
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应用备注
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ELISA: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- ITPKA (Inositol-Trisphosphate 3-Kinase A (ITPKA))
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别名
- ITPKA / IP3 3-Kinase A
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背景
- ITPKA regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68 % identical in the C-terminus region.Synonyms: 4, 5-trisphosphate 3-kinase A, IP3KA, Inositol 1, Inositol-trisphosphate 3-kinase A, InsP 3-kinase A
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基因ID
- 3706, 9606
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UniProt
- P23677
抗原
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