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CIB2 抗体 (N-Term)

This 兔 多克隆 anti-CIB2 antibody specifically detects CIB2 in WB, IHC (p) 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN360675
发货至: 中国
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Quick Overview for CIB2 抗体 (N-Term) (ABIN360675)

抗原

See all CIB2 抗体
CIB2 (Calcium And Integrin Binding Family Member 2 (CIB2))

适用

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宿主

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克隆类型

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多克隆

标记

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This CIB2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody reacts to KIP2.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human KIP2.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    CIB2 (Calcium And Integrin Binding Family Member 2 (CIB2))

    别名

    CIB2

    背景

    DNA-dependent protein kinases (DNA-PK) play a role in the repair of double-strand DNA breaks and in the process of V(D)J recombination during lymphoid development. By EST database searching for sequences homologous to the DNA-PK gene KIP/CIB and 5-prime RACE, Seki, N et al. isolated a full-length cDNA, which they designated as KIP2, from a human fetal brain cDNA library. KIP2 encodes a deduced 187-amino acid protein with a predicted molecular mass of 22 kD. The KIP2 protein shares 46 % , 39 %, and 30 % sequence identity with the calcium-binding proteins KIP/CIB, calcineurin B and calmodulin respectively. KIP2 contains two EF-hand motifs and a helix-loop-helix motif involved in coordinating the calcium ion, indicating that KIP2 may also bind calcium. KIP2 is ubiquitously expressed in various human tissues.Synonyms: CIB2, Calcium and integrin-binding family member 2, KIP 2, KIP2, Kinase-interacting protein 2

    基因ID

    10518, 9606

    UniProt

    O75838
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