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ZAK 抗体 (Middle Region)

This anti-ZAK antibody is a 兔 多克隆 antibody detecting ZAK in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN360531
发货至: 中国

Quick Overview for ZAK 抗体 (Middle Region) (ABIN360531)

抗原

See all ZAK 抗体
ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))

适用

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  • 33
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宿主

  • 52
  • 6

克隆类型

  • 52
  • 6
多克隆

标记

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  • 1
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This ZAK antibody is un-conjugated

应用范围

  • 32
  • 25
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  • 3
  • 1
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 8
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    • 4
    • 3
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    • 1
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    Middle Region

    特异性

    This antibody reacts to MLKLAK.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human MLKLAK.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))

    别名

    MLTK

    背景

    MLKLAK is a member of the MAPKKK family of signal transduction molecules. It possesses an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity.Synonyms: Cervical cancer suppressor gene 4 protein, HCCS-4, HCCS4, MLK-like mitogen-activated protein triple kinase, MLKLAK, Mitogen-activated protein kinase kinase kinase MLT, ZAK

    基因ID

    51776, 9606

    UniProt

    Q9NYL2
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