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PIK3R2 抗体 (Tyr467)

This anti-PIK3R2 antibody is a 兔 多克隆 antibody detecting PIK3R2 in WB 和 EIA. Suitable for 人.
产品编号 ABIN360466
发货至: 中国

Quick Overview for PIK3R2 抗体 (Tyr467) (ABIN360466)

抗原

See all PIK3R2 (PI3K p85b) 抗体
PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))

适用

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宿主

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克隆类型

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多克隆

标记

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This PIK3R2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Tyr467

    特异性

    This antibody reacts to PIK3R2.

    纯化方法

    Protein A column, followed by peptide affinity purification

    免疫原

    This antibody is generated from rabbits immunized with a peptide corresponding to amino acid residues surrounding Y467 of human PIK3R2.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))

    别名

    PIK3R2

    背景

    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.PIK3R2 binds to activated Protein Tyrosine Kinases, which are phosphorylated, through its SH2 domain, and acts as an adaptor, mediating the association of the P110 catalytic unit to the plasma membrane.Synonyms: PI 3 Kinase p85 beta, PI3-kinase regulatory subunit beta, PI3K regulatory subunit beta, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, Phosphatidylinositol 3-kinase regulatory subunit beta

    基因ID

    5296, 9606

    UniProt

    O00459

    途径

    VEGF Signaling, BCR Signaling
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