PRKG2 抗体 (C-Term)
Quick Overview for PRKG2 抗体 (C-Term) (ABIN360423)
抗原
See all PRKG2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antiobdy reacts to cGKII.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human cGKII.
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亚型
- Ig Fraction
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anti-Protein Kinase, CGMP-Dependent, Type II (PRKG2) (AA 714-744), (C-Term) antibody
PRKG2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01036 unconjugated
anti-Protein Kinase, CGMP-Dependent, Type II (PRKG2) (Internal Region) antibodyPRKG2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CGMP-Dependent, Type II (PRKG2) (Ser363), (Thr359) antibodyPRKG2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CGMP-Dependent, Type II (PRKG2) antibodyPRKG2 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CGMP-Dependent, Type II (PRKG2) (Ser126) antibodyPRKG2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CGMP-Dependent, Type II (PRKG2) (AA 453-728) antibodyPRKG2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CGMP-Dependent, Type II (PRKG2) (AA 1-100) antibodyPRKG2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase, CGMP-Dependent, Type II (PRKG2) (N-Term) antibodyPRKG2 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CGMP-Dependent, Type II (PRKG2) (N-Term) antibodyPRKG2 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Immunohistochemistry: 1/50 - 1/100. Western Blot: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- PRKG2 (Protein Kinase, CGMP-Dependent, Type II (PRKG2))
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别名
- CGK2
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背景
- CGKII is thought to play a key role in a diverse set of physiological pathway. cGKII may mediate intestinal secretion of water and electrolytes induced by the E. coli toxin STa and the intestinal peptide guanylin. Edentification of the pathway that mediates intestinal fluid secretion by E. coli STa has potential medical implications because STa causes traveler's diarrhea and about 50 % of infant mortality in developing countries. Transfection experiments in human cells disclose that cGKII phosphorylates SOX9 and attenuates SOX9 function by inhibiting its nuclear entry. Impaired differentiation of cultured KMI chondrocytes can be restored by silencing Sox9 by RNA interference. cGKII is postulated to be a molecular switch that couples the cessation of proliferation and the start of hypertrophic chondrocyte differentiation through attenuating SOX9 function.Synonyms: PRKG2, PRKGR2, Type II cGMP-dependent protein kinase, cGKII, cGMP-dependent protein kinase 2
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基因ID
- 5593, 9606
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UniProt
- Q13237
抗原
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