PAK6 抗体 (AA 131-146)
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北京 101111
Quick Overview for PAK6 抗体 (AA 131-146) (ABIN360326)
抗原
See all PAK6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 131-146
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特异性
- This antibody reacts to PAK6.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from aa 131~146 of human PAK6.
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亚型
- Ig Fraction
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anti-P21-Activated Kinase 6 (PAK6) (AA 268-297) antibody
PAK6 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 6 (PAK6) (AA 1-681) antibodyPAK6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 6 (PAK6) (AA 268-297) antibodyPAK6 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB31991 unconjugated
anti-P21-Activated Kinase 6 (PAK6) (AA 1-270) antibodyPAK6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 6 (PAK6) (Linker Domain) antibodyPAK6 适用: 人, 马, 犬, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 6 (PAK6) (N-Term) antibodyPAK6 适用: 人, 小鼠, 大鼠, 马, Cow, 犬, 兔, 猴, Bat, 小鸡 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 6 (PAK6) (AA 275-305), (Middle Region) antibodyPAK6 适用: 人 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 6 (PAK6) (AA 16-32), (N-Term) antibodyPAK6 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 6 (PAK6) (AA 116-146) antibodyPAK6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 6 (PAK6) (Center) antibodyPAK6 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunoprecipitation: 1/100. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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: "Pyruvate kinase M2 promotes pancreatic ductal adenocarcinoma invasion and metastasis through phosphorylation and stabilization of PAK2 protein." in: Oncogene, Vol. 37, Issue 13, pp. 1730-1742, (2019) (PubMed).
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: "Pyruvate kinase M2 promotes pancreatic ductal adenocarcinoma invasion and metastasis through phosphorylation and stabilization of PAK2 protein." in: Oncogene, Vol. 37, Issue 13, pp. 1730-1742, (2019) (PubMed).
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- PAK6 (P21-Activated Kinase 6 (PAK6))
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别名
- PAK6
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背景
- The PAK6 protein shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. PAK6 was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.Synonyms: PAK-5, PAK-6, PAK5, Serine/threonine-protein kinase PAK 6, p21-activated kinase 6
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基因ID
- 56924
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NCBI登录号
- NP_001122100
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UniProt
- Q9NQU5
抗原
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