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LCK 抗体 (N-Term)

Name: LCK 抗体 (N-Term)
SKU: ABIN359986
Availability: OutOfStock

LCK 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (N-Term) antibody (ABIN359986) (LCK 抗体 (N-Term))

Image no. 2 for anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (N-Term) antibody (ABIN359986) (LCK 抗体 (N-Term))

2 images

产品编号 ABIN359986

发货至: 中国

Datasheet as PDF

抗原 See all LCK 抗体

LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
抗原表位
28

16

15

11

10

8

8

8

7

5

5

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
168

95

60

9

6

6

4

4

4

3

3

2

1
人, 小鼠
宿主
152

14

2
兔
Compatible Secondaries
克隆类型
147

22
多克隆
标记
97

10

10

7

6

5

4

4

4

4

4

4

2

2

2

2

2
This LCK antibody is un-conjugated
应用范围
130

88

30

29

24

20

16

14

13

10

3

3

2

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

特异性

This antibody reacts to LCK (LSK).

纯化方法

Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

免疫原

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human LSK.

亚型

Ig Fraction

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anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-240) antibody
LCK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 22-36) antibody
LCK 适用: 人 WB, FACS, IP, ICC 宿主: 小鼠 Monoclonal LCK-01 unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 23-52) antibody
LCK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) antibody
LCK 适用: 人 ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 468-506), (C-Term) antibody
LCK 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 480-509) antibody
LCK 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 421-509) antibody
LCK 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-539) antibody
LCK 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-100) antibody
LCK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H5 unconjugated

应用备注

ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
状态

Liquid

浓度

0.25 mg/mL

缓冲液

PBS with 0.09 % (W/V) sodium azide

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
抗原

LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))

别名

LCK (LCK 产品)

别名

zgc:136695 antibody, LCK antibody, Hck-3 antibody, Lsk antibody, Lskt antibody, p56 antibody, p56Lck antibody, LSK antibody, YT16 antibody, p56lck antibody, pp58lck antibody, P56LCK antibody, tkl antibody, Lck1 antibody, Lcktkr antibody, LCK proto-oncogene, Src family tyrosine kinase antibody, lymphocyte protein tyrosine kinase antibody, lck antibody, LCK antibody, Lck antibody

背景

LSK, which belongs to the SRC subfamily of Tyr protein kinases, may participate in antigen-induced T-cell activation. It binds to phosphatidylinositol 3'-kinase (PI3K) from T lymphocytes through its SH3 domain and to the tyrosine phosphorylated form of KHDRBS1/p70 through its SH2 domain. LSK is bound to the cytoplasmic domain of either CD4 or CD8. This protein is involved in leukemias by a chromosomal translocation t(1,7)(p34,q34) which involves LCK and T-cell receptor beta chain (TCRB) genes.Synonyms: LSK, Lymphocyte cell-specific protein-tyrosine kinase, Proto-oncogene tyrosine-protein kinase LCK, T cell-specific protein-tyrosine kinase, p56-LCK

基因ID

3932, 9606

UniProt

P06239

途径

TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling