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PTPN7 抗体 (Ser44)

The 兔 多克隆 anti-PTPN7 antibody is suitable to detect PTPN7 in samples from 人. It has been validated for WB, IHC (p) 和 EIA.
产品编号 ABIN359780
发货至: 中国
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Quick Overview for PTPN7 抗体 (Ser44) (ABIN359780)

抗原

See all PTPN7 抗体
PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))

适用

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宿主

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克隆类型

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多克隆

标记

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This PTPN7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Ser44

    特异性

    This antibody reacts to PTPN7.

    纯化方法

    Protein A column, followed by peptide affinity purification

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S44 of human PTPN7.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))

    别名

    PTPN7 / HEPTP

    背景

    PTPN7 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN7 is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP has been shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which is thought to function through dephosphorylating the molecules related to MAP kinase pathway.Synonyms: Hematopoietic protein-tyrosine phosphatase, Protein-tyrosine phosphatase LC-PTP, Tyrosine-protein phosphatase non-receptor type 7

    基因ID

    5778, 9606

    UniProt

    P35236
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