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APOE 抗体 (C-Term)

The 兔 多克隆 anti-APOE antibody (ABIN359760) specifically detects APOE in WB, IHC (p) 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN359760
发货至: 中国
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Room 801-803
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Quick Overview for APOE 抗体 (C-Term) (ABIN359760)

抗原

See all APOE 抗体
APOE (Apolipoprotein E (APOE))

适用

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宿主

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克隆类型

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  • 55
多克隆

标记

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This APOE antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody recognizes Apolipoprotein E (Apo E) at C-term.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of Human APOE.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blot: 1/50-1/100. Immunohistochemistry on paraffin sections: 1/10-1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    APOE (Apolipoprotein E (APOE))

    别名

    Apolipoprotein E (Apo E)

    背景

    Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III),in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.Synonyms: Apo-E, ApoE

    基因ID

    348, 9606

    UniProt

    P02649

    途径

    Regulation of Cell Size, Lipid Metabolism
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