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MAPK15 抗体 (N-Term)

This anti-MAPK15 antibody is a 兔 多克隆 antibody detecting MAPK15 in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN359709
发货至: 中国

Quick Overview for MAPK15 抗体 (N-Term) (ABIN359709)

抗原

See all MAPK15 抗体
MAPK15 (Mitogen-Activated Protein Kinase 15 (MAPK15))

适用

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宿主

  • 35
  • 9

克隆类型

  • 37
  • 7
多克隆

标记

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This MAPK15 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 11
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    N-Term

    特异性

    This antibody reacts to MAPK15 (ERK8).

    纯化方法

    Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ERK8.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    MAPK15 (Mitogen-Activated Protein Kinase 15 (MAPK15))

    别名

    MAPK15

    背景

    The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.Synonyms: ERK8, Extracellular signal-regulated kinase 8, Mitogen-activated protein kinase 15

    基因ID

    225689, 9606

    UniProt

    Q8TD08
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