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TGIF1 抗体 (Middle Region)

The 兔 多克隆 anti-TGIF1 antibody (ABIN359523) specifically detects TGIF1 in WB 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN359523
发货至: 中国
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Quick Overview for TGIF1 抗体 (Middle Region) (ABIN359523)

抗原

See all TGIF1 抗体
TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

适用

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宿主

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克隆类型

  • 35
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多克隆

标记

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This TGIF1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Middle Region

    特异性

    This antibody detects TGIF at center.

    纯化方法

    PBS with 0.09% (W/V) sodium azide

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human TGIF1.

    亚型

    Ig Fraction
  • 应用备注

    ELISA 1: 1,000. Western blot 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

    别名

    TGIF1

    背景

    TGIF1 is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.Synonyms: 5'-TG-3'-interacting factor 1, Homeobox protein TGIF1, TGIF

    分子量

    43044 Da

    基因ID

    7050, 9606

    UniProt

    Q15583

    途径

    Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation
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