TGIF1 抗体 (Middle Region)
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Quick Overview for TGIF1 抗体 (Middle Region) (ABIN359523)
抗原
See all TGIF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- This antibody detects TGIF at center.
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纯化方法
- PBS with 0.09% (W/V) sodium azide
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human TGIF1.
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亚型
- Ig Fraction
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应用备注
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ELISA 1: 1,000. Western blot 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))
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别名
- TGIF1
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背景
- TGIF1 is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.Synonyms: 5'-TG-3'-interacting factor 1, Homeobox protein TGIF1, TGIF
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分子量
- 43044 Da
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基因ID
- 7050, 9606
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UniProt
- Q15583
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途径
- Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation
抗原
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