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Prohibitin 2 抗体 (N-Term)

This anti-Prohibitin 2 antibody is a 兔 多克隆 antibody detecting Prohibitin 2 in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN359501
发货至: 中国

Quick Overview for Prohibitin 2 抗体 (N-Term) (ABIN359501)

抗原

See all Prohibitin 2 (PHB2) 抗体
Prohibitin 2 (PHB2)

适用

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宿主

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克隆类型

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多克隆

标记

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This Prohibitin 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody detects REA (PHB2) at N-term.

    纯化方法

    Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PHB2.

    亚型

    Ig Fraction
  • 应用备注

    ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Prohibitin 2 (PHB2)

    别名

    Prohibitin-2

    背景

    PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging.Synonyms: B-cell receptor-associated protein BAP37, BAP, BAP37, D-prohibitin, PHB2, REA, Repressor of estrogen receptor activity

    分子量

    33165 Da

    基因ID

    11331, 9606

    UniProt

    Q99623

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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