CDKL5 抗体 (C-Term)
Quick Overview for CDKL5 抗体 (C-Term) (ABIN359452)
抗原
See all CDKL5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects CDKL5 (STK9) at C-term.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human STK9.
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亚型
- Ig Fraction
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anti-Cyclin-Dependent Kinase-Like 5 (CDKL5) (AA 722-831) antibody
CDKL5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D9 unconjugated
anti-Cyclin-Dependent Kinase-Like 5 (CDKL5) (Internal Region) antibodyCDKL5 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase-Like 5 (CDKL5) (AA 982-1012), (C-Term) antibodyCDKL5 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase-Like 5 (CDKL5) (AA 790-921) antibodyCDKL5 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase-Like 5 (CDKL5) (AA 982-1012), (C-Term) antibodyCDKL5 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3556 unconjugated
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应用备注
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ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- CDKL5 (Cyclin-Dependent Kinase-Like 5 (CDKL5))
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别名
- CDKL5 / STK9
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背景
- Defects in STK9, a dual-specificity serine/threonine kinase, are a cause of atypical Rett syndrome. Rett syndrome is an X-linked dominant disease. It is a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. Patients appear to develop normally until 6 to 18 months of age, then gradually lose speech and purposeful hand movements and develop microcephaly, seizures, autism, ataxia, intermittent hyperventilation, and stereotypic hand movements. After initial regression, the condition stabilizes and patients usually survive into adulthood. Rett syndrome due to CDKL5-associated mutations is characterized by a severe early-onset phenotype and atypical features such as infantile spasms.Synonyms: Cyclin-dependent kinase-like 5, Serine/threonine protein kinase 9
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分子量
- 115537 Da
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基因ID
- 6792, 9606
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UniProt
- O76039
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途径
- Regulation of Cell Size
抗原
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