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PDXK 抗体 (C-Term)

PDXK 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN359335
发货至: 中国
  • 抗原 See all PDXK 抗体
    PDXK (Pyridoxal Kinase (PDXK))
    抗原表位
    • 8
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 45
    • 32
    • 21
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 41
    • 7
    克隆类型
    • 43
    • 5
    多克隆
    标记
    • 29
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDXK antibody is un-conjugated
    应用范围
    • 46
    • 14
    • 13
    • 9
    • 8
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to PDXK.
    纯化方法
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PDXK.
    亚型
    Ig Fraction
    Top Product
    Discover our top product PDXK Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    PDXK (Pyridoxal Kinase (PDXK))
    别名
    Pyridoxal Kinase / PDXK (PDXK 产品)
    别名
    C21orf124 antibody, C21orf97 antibody, PKH antibody, PNK antibody, 2310036D04Rik antibody, AA119688 antibody, C77999 antibody, Pdxk antibody, PSPTO5521 antibody, DDBDRAFT_0190079 antibody, DDBDRAFT_0191114 antibody, DDB_0190079 antibody, DDB_0191114 antibody, ATSOS4 antibody, K18L3.1 antibody, K18L3_1 antibody, SALT OVERLY SENSITIVE 4 antibody, pdxk antibody, si:dkey-263m10.2 antibody, si:dz69g10.1 antibody, cb1056 antibody, pdxkl antibody, si:dkey-281i8.2 antibody, wu:fa55a03 antibody, wu:fb10c12 antibody, zgc:101900 antibody, pyridoxal kinase antibody, pyridoxal (pyridoxine, vitamin B6) kinase antibody, Pyridoxal kinase antibody, pfkB-like carbohydrate kinase family protein antibody, pyridoxal (pyridoxine, vitamin B6) kinase b antibody, pyridoxal (pyridoxine, vitamin B6) kinase a antibody, PDXK antibody, Pdxk antibody, pdxY antibody, pdxK antibody, Bphyt_1541 antibody, pykA antibody, Kfla_4736 antibody, Kvar_1290 antibody, Mrub_2507 antibody, BC1002_1103 antibody, Fbal_1661 antibody, Lbys_0710 antibody, Intca_0131 antibody, Deima_3190 antibody, Mesop_1158 antibody, LOC100283562 antibody, pdxk antibody, SOS4 antibody, pdxkb antibody, pdxka antibody
    背景
    Pyridoxal kinase (PDXK) converts vitamin B6 to pyridoxal-5-phosphate (PLP), an essential cofactor in the intermediate metabolism of amino acids and neurotransmitters. The PDXK gene encodes a 312-amino acid polypeptide, and expression of the cDNA reveals pyridoxal kinase activity. Northern blot analysis revealed that a major 1.5-kb PDXK transcript is expressed in all tissues tested. The expression of PDXK shows circadian oscillations. The expression of Pdxk in mouse liver and brain is regulated by the 3 PAR bZIP transcription factors, Dbp, Hlf, and Tef, which also show circadian oscillations in expression. Mice devoid of all 3 transcription factors show decreased levels of brain PLP, serotonin, and dopamine, and are highly susceptible to frequently lethal generalized spontaneous and audiogenic epilepsies.Synonyms: C21orf124, C21orf97, PKH, PNK, PRED79, Pyridoxine kinase
    基因ID
    8566, 9606
    UniProt
    O00764
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