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PDXK 抗体 (C-Term)

Name: PDXK 抗体 (C-Term)
SKU: ABIN359335
Availability: OutOfStock

PDXK 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

Western blot analysis of anti-PDXK in HepG2 cell line lysate (35ug/lane). (PDXK 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (PDXK 抗体 (C-Term))

IHC (p)

2 images

产品编号 ABIN359335

发货至: 中国

Datasheet as PDF

抗原 See all PDXK 抗体

PDXK (Pyridoxal Kinase (PDXK))
抗原表位
8

6

3

2

2

1

1

1

1

1

1

1

1

1
C-Term
适用
51

31

21

4

4

3

3

3

2

2

1

1

1
人
宿主
47

7
兔
Compatible Secondaries
克隆类型
49

5
多克隆
标记
29

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This PDXK antibody is un-conjugated
应用范围
46

14

13

11

6

5

4

3

3

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

特异性

This antibody reacts to PDXK.

纯化方法

Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

免疫原

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PDXK.

亚型

Ig Fraction

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anti-Pyridoxal Kinase (PDXK) (AA 29-285) antibody
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anti-Pyridoxal Kinase (PDXK) (AA 35-251) antibody
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anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibody
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anti-Pyridoxal Kinase (PDXK) (AA 51-160) antibody
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anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibody
PDXK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G6 unconjugated

anti-Pyridoxal Kinase (PDXK) antibody
PDXK 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibody
PDXK 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibody
PDXK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

应用备注

ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
状态

Liquid

浓度

0.25 mg/mL

缓冲液

PBS with 0.09 % (W/V) sodium azide

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
抗原

PDXK (Pyridoxal Kinase (PDXK))

别名

Pyridoxal Kinase / PDXK (PDXK 产品)

背景

Pyridoxal kinase (PDXK) converts vitamin B6 to pyridoxal-5-phosphate (PLP), an essential cofactor in the intermediate metabolism of amino acids and neurotransmitters. The PDXK gene encodes a 312-amino acid polypeptide, and expression of the cDNA reveals pyridoxal kinase activity. Northern blot analysis revealed that a major 1.5-kb PDXK transcript is expressed in all tissues tested. The expression of PDXK shows circadian oscillations. The expression of Pdxk in mouse liver and brain is regulated by the 3 PAR bZIP transcription factors, Dbp, Hlf, and Tef, which also show circadian oscillations in expression. Mice devoid of all 3 transcription factors show decreased levels of brain PLP, serotonin, and dopamine, and are highly susceptible to frequently lethal generalized spontaneous and audiogenic epilepsies.Synonyms: C21orf124, C21orf97, PKH, PNK, PRED79, Pyridoxine kinase

基因ID

8566, 9606

UniProt

O00764