PDXK 抗体 (C-Term)
Quick Overview for PDXK 抗体 (C-Term) (ABIN359335)
抗原
See all PDXK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to PDXK.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PDXK.
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亚型
- Ig Fraction
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anti-Pyridoxal Kinase (PDXK) (AA 29-253) antibody
PDXK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 29-285) antibodyPDXK 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 35-251) antibodyPDXK 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) antibodyPDXK 适用: 人 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 5H5 unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibodyPDXK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 51-160) antibodyPDXK 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibodyPDXK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibodyPDXK 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) antibodyPDXK 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibodyPDXK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- PDXK (Pyridoxal Kinase (PDXK))
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别名
- Pyridoxal Kinase / PDXK
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背景
- Pyridoxal kinase (PDXK) converts vitamin B6 to pyridoxal-5-phosphate (PLP), an essential cofactor in the intermediate metabolism of amino acids and neurotransmitters. The PDXK gene encodes a 312-amino acid polypeptide, and expression of the cDNA reveals pyridoxal kinase activity. Northern blot analysis revealed that a major 1.5-kb PDXK transcript is expressed in all tissues tested. The expression of PDXK shows circadian oscillations. The expression of Pdxk in mouse liver and brain is regulated by the 3 PAR bZIP transcription factors, Dbp, Hlf, and Tef, which also show circadian oscillations in expression. Mice devoid of all 3 transcription factors show decreased levels of brain PLP, serotonin, and dopamine, and are highly susceptible to frequently lethal generalized spontaneous and audiogenic epilepsies.Synonyms: C21orf124, C21orf97, PKH, PNK, PRED79, Pyridoxine kinase
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基因ID
- 8566, 9606
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UniProt
- O00764
抗原
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