PANK2 抗体 (N-Term)
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北京 101111
Quick Overview for PANK2 抗体 (N-Term) (ABIN359320)
抗原
See all PANK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to PANK2.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PANK2.
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亚型
- Ig Fraction
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anti-Pantothenate Kinase 2 (PANK2) antibody
PANK2 适用: 人, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 3H9 unconjugated
anti-Pantothenate Kinase 2 (PANK2) (AA 205-260) antibodyPANK2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2B12 unconjugated
anti-Pantothenate Kinase 2 (PANK2) (AA 437-490) antibodyPANK2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pantothenate Kinase 2 (PANK2) (N-Term) antibodyPANK2 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pantothenate Kinase 2 (PANK2) (AA 459-508) antibodyPANK2 适用: 人, 大鼠, 犬, Cow, 马, 绵羊, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Pantothenate Kinase 2 (PANK2) (AA 300-400) antibodyPANK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Pantothenate Kinase 2 (PANK2) (AA 65-95), (N-Term) antibodyPANK2 适用: 人 WB 宿主: 兔 Polyclonal RB5486 unconjugated
anti-Pantothenate Kinase 2 (PANK2) (AA 180-210) antibodyPANK2 适用: 人 WB 宿主: 兔 Polyclonal RB5487 unconjugated
anti-Pantothenate Kinase 2 (PANK2) antibodyPANK2 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 3G4 unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- PANK2 (Pantothenate Kinase 2 (PANK2))
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别名
- PANK2
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背景
- Pantothenate kinase is an essential regulatory enzyme in CoA biosynthesis, catalyzing the cytosolic phosphorylation of pantothenate (vitamin B5), N-pantothenoylcysteine, and pantetheine. CoA is the major acyl carrier, playing a central role in intermediary and fatty acid metabolism. In both yeast and fly, each with only 1 pantothenate kinase gene, the null mutant is inviable. Mutations in PANK2 are the cause of pantothenate kinase-associated neurodegeneration (PKAN), formerly known as Hallervorden-Spatz syndrome (HSS). PKAN is an autosomal recessive neurodegenerative disorder associated with iron accumulation in the brain. Mutations in PANK2 are the cause of hypoprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration (HARP).Synonyms: C20orf48, Pantothenate kinase 2 mitochondrial, Pantothenic acid kinase 2
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基因ID
- 80025, 9606
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UniProt
- Q9BZ23
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途径
- Ribonucleoside Biosynthetic Process
抗原
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