NME3 抗体 (AA 59-88)
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Quick Overview for NME3 抗体 (AA 59-88) (ABIN359315)
抗原
See all NME3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 59-88
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特异性
- This antibody recognizes NME3.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59~88 from the center region of Human NME3.
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亚型
- Ig Fraction
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- NME3 (NME/NM23 Nucleoside Diphosphate Kinase 3 (NME3))
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别名
- NME3
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背景
- NME3 mRNA is preferentially expressed at early stages of myeloid differentiation of highly purified CD34(+) cells. Its constitutive expression in a myeloid precursor line, which is growth-factor dependent for both proliferation and differentiation, results in inhibition of granulocytic differentiation induced by granulocyte colony-stimulating factor and causes apoptotic cell death. These results appear consistent with a role for the NME3 gene in normal hematopoiesis and raise the possibility that its overexpression contributes to differentiation arrest, a feature of blastic transformation in chronic myelogenous leukemia.Synonyms: DR-nm23, NDK 3, NDK-3, NDK3, NDP kinase 3, NDPKC, Nucleoside diphosphate kinase 3, Nucleoside diphosphate kinase C, nm23-H3
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基因ID
- 4832, 9606
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UniProt
- Q13232
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途径
- Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
抗原
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