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NME3 抗体 (AA 59-88)

The 兔 多克隆 anti-NME3 antibody is suitable to detect NME3 in samples from 人. It has been validated for WB, IHC (p) 和 EIA.
产品编号 ABIN359315
发货至: 中国
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Quick Overview for NME3 抗体 (AA 59-88) (ABIN359315)

抗原

See all NME3 抗体
NME3 (NME/NM23 Nucleoside Diphosphate Kinase 3 (NME3))

适用

  • 45
  • 12
  • 2

宿主

  • 42
  • 5

克隆类型

  • 34
  • 13
多克隆

标记

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This NME3 antibody is un-conjugated

应用范围

  • 32
  • 23
  • 14
  • 11
  • 5
  • 5
  • 4
  • 2
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  • 1
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 59-88

    特异性

    This antibody recognizes NME3.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59~88 from the center region of Human NME3.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    NME3 (NME/NM23 Nucleoside Diphosphate Kinase 3 (NME3))

    别名

    NME3

    背景

    NME3 mRNA is preferentially expressed at early stages of myeloid differentiation of highly purified CD34(+) cells. Its constitutive expression in a myeloid precursor line, which is growth-factor dependent for both proliferation and differentiation, results in inhibition of granulocytic differentiation induced by granulocyte colony-stimulating factor and causes apoptotic cell death. These results appear consistent with a role for the NME3 gene in normal hematopoiesis and raise the possibility that its overexpression contributes to differentiation arrest, a feature of blastic transformation in chronic myelogenous leukemia.Synonyms: DR-nm23, NDK 3, NDK-3, NDK3, NDP kinase 3, NDPKC, Nucleoside diphosphate kinase 3, Nucleoside diphosphate kinase C, nm23-H3

    基因ID

    4832, 9606

    UniProt

    Q13232

    途径

    Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
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