STRADA 抗体 (N-Term)
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Quick Overview for STRADA 抗体 (N-Term) (ABIN359296)
抗原
See all STRADA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to LYK5.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human LYK5.
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亚型
- Ig Fraction
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anti-STE20-Related Kinase Adaptor alpha (STRADA) (AA 303-346), (C-Term) antibody
STRADA 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB47810 unconjugated
anti-STE20-Related Kinase Adaptor alpha (STRADA) (AA 251-346) antibodySTRADA 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 4E4 unconjugated
anti-STE20-Related Kinase Adaptor alpha (STRADA) (AA 12-41), (N-Term) antibodySTRADA 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB8539 unconjugated
anti-STE20-Related Kinase Adaptor alpha (STRADA) antibodySTRADA 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor alpha (STRADA) (AA 1-348) antibodySTRADA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor alpha (STRADA) (AA 25-210) antibodySTRADA 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor alpha (STRADA) (Internal Region) antibodySTRADA 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor alpha (STRADA) (Internal Region) antibodySTRADA 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor alpha (STRADA) (AA 25-210) antibodySTRADA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor alpha (STRADA) (N-Term) antibodySTRADA 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- STRADA (STE20-Related Kinase Adaptor alpha (STRADA))
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别名
- STRAD alpha / LYK5
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背景
- LYK5, also STE20-related Adaptor Protein (STRAD) are members of STE-20 like kinase family that are known to stimulate MAPK pathways by directly activating MAPKKK. LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRAD-LKB1 interaction results in phosphorylation of STRAD and enhanced autophosphorylation of LKB1.Synonyms: NY-BR-96, STE20-related adapter protein, STE20-related kinase adapter protein alpha, STRAD, STRADA
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基因ID
- 92335, 9606
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UniProt
- Q7RTN6
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途径
- AMPK Signaling
抗原
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