ADK 抗体 (N-Term)
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Quick Overview for ADK 抗体 (N-Term) (ABIN359195)
抗原
See all ADK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to ADK.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ADK.
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亚型
- Ig Fraction
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anti-Adenosine Kinase (ADK) (AA 1-361) antibody
ADK 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) antibodyADK 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) (AA 200-345) antibodyADK 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) antibodyKO Validated ADK 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) (AA 165-351) antibodyADK 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) (AA 18-256) antibodyADK 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) (AA 165-351) antibodyADK 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) (AA 322-352), (C-Term) antibodyADK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB05395 unconjugated
anti-Adenosine Kinase (ADK) (AA 1-345) antibodyADK 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 1103CT3-4-3 unconjugated
anti-Adenosine Kinase (ADK) (AA 236-345) antibodyADK 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- ADK (Adenosine Kinase (ADK))
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别名
- Adenosine Kinase (AK)
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背景
- Adenosine kinase (ATP:adenosine 5-prime-phosphotransferase) is an abundant enzyme in mammalian tissues that catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a potentially important regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of ADK could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as antiinflammatory agents. The encoded protein does not present any sequence similarities to other well-characterized mammalian nucleoside kinases. In contrast, 2 regions were identified with significant sequence identity to microbial ribokinase and fructokinases and a bacterial inosine/guanosine kinase. Thus, ADK is a structurally distinct mammalian nucleoside kinase that appears to be akin to sugar kinases of microbial origin. Animal studies have demonstrated that a deficiency of adenosine metabolism a powerful contributor to the development of neonatal hepatic steatosis, providing a model for the rapid development of postnatally lethal fatty liver.Synonyms: ADK, Adenosine 5'-phosphotransferase
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基因ID
- 132, 9606
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UniProt
- P55263
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途径
- Ribonucleoside Biosynthetic Process
抗原
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