CERK 抗体 (C-Term)
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Quick Overview for CERK 抗体 (C-Term) (ABIN359190)
抗原
See all CERK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to CERK.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CERK.
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亚型
- Ig Fraction
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anti-Ceramide Kinase (CERK) (AA 212-478) antibody
CERK 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ceramide Kinase (CERK) (AA 487-516), (C-Term) antibodyCERK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB5271 unconjugated
anti-Ceramide Kinase (CERK) antibodyCERK 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ceramide Kinase (CERK) (AA 1-201) antibodyCERK 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ceramide Kinase (CERK) (AA 1-201) antibodyCERK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ceramide Kinase (CERK) (AA 487-516) antibodyCERK 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ceramide Kinase (CERK) (C-Term) antibodyCERK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- CERK (Ceramide Kinase (CERK))
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别名
- Ceramide Kinase
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背景
- Ceramide kinases convert the sphingolipid metabolite ceramide into ceramide-1-phosphate, both key mediators of cellular apoptosis and survival. Ceramide metabolism plays an essential role in the viability of neuronal cells, the membranes of which are particularly rich in sphingolipids. CERK catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. This enzyme acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8 dihydroceramide), and to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. High level expression is noted in heart, brain, skeletal muscle, kidney and liver, moderate expression in peripheral blood leukocytes and thymus, and low expression in spleen, small intestine, placenta and lung.Synonyms: Acylsphingosine kinase, KIAA1646, LK4, Lipid kinase 4, hCERK
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基因ID
- 64781, 9606
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UniProt
- Q8TCT0
抗原
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