CKMT1B 抗体 (N-Term)
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Quick Overview for CKMT1B 抗体 (N-Term) (ABIN359153)
抗原
See all CKMT1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 62-92, N-Term
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特异性
- This antibody recognizes Creatine kinase MT (CKMT1).
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纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62~92 amino acids from the N-terminal region of Human CKMT1. Genename: CKMT1B, CKMT1A
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亚型
- Ig Fraction
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))
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别名
- CKMT
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背景
- Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase.Synonyms: Acidic-type mitochondrial creatine kinase, CKMT1A, CKMT1B, Creatine kinase U, Mia-CK, U-MtCK, ubiquitous mitochondrial Creatine kinase
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基因ID
- 1159, 9606
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UniProt
- P12532
抗原
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