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CKMT1B 抗体 (N-Term)

This anti-CKMT1B antibody is a 兔 多克隆 antibody detecting CKMT1B in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN359153
发货至: 中国

Quick Overview for CKMT1B 抗体 (N-Term) (ABIN359153)

抗原

See all CKMT1B 抗体
CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This CKMT1B antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 62-92, N-Term

    特异性

    This antibody recognizes Creatine kinase MT (CKMT1).

    纯化方法

    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62~92 amino acids from the N-terminal region of Human CKMT1. Genename: CKMT1B, CKMT1A

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Flow cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

    别名

    CKMT

    背景

    Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase.Synonyms: Acidic-type mitochondrial creatine kinase, CKMT1A, CKMT1B, Creatine kinase U, Mia-CK, U-MtCK, ubiquitous mitochondrial Creatine kinase

    基因ID

    1159, 9606

    UniProt

    P12532
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