Ketohexokinase 抗体 (N-Term)
Quick Overview for Ketohexokinase 抗体 (N-Term) (ABIN359149)
抗原
See all Ketohexokinase (KHK) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to Ketohexokinase (KHK).
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human KHK.
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亚型
- Ig Fraction
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anti-Ketohexokinase (KHK) (AA 1-298) antibody
KHK 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 1H6-2B6 unconjugated
anti-Ketohexokinase (KHK) (AA 1-298) antibodyKHK 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ketohexokinase (KHK) (AA 1-298) antibodyKHK 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Ketohexokinase (KHK) (AA 1-298) antibodyKHK 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal S1 unconjugated
anti-Ketohexokinase (KHK) (AA 1-298) antibodyKHK 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ketohexokinase (KHK) (Internal Region) antibodyVerified KHK 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Ketohexokinase (KHK) (AA 201-297) antibodyKHK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B1 unconjugated
anti-Ketohexokinase (KHK) (AA 251-281), (C-Term) antibodyKHK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB05412 unconjugated
anti-Ketohexokinase (KHK) (C-Term) antibodyKHK 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ketohexokinase (KHK) (N-Term) antibodyKHK 适用: 人, Cow, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Ketohexokinase (KHK)
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别名
- Ketohexokinase
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背景
- Ketohexokinase (KHK), or fructokinase, catalyzes conversion of fructose to fructose-1-phosphate. Splice variant 1 is the highly active form found in liver, renal cortex, and small intestine, while splice variant 2 is the lower activity form found in most other tissues. KHK, like glucokinase (GCK) and glucokinase regulator (GCKR), is present in both liver and pancreatic islets. The inhibition of GCK by GCKR is blocked by binding of fructose-1-phosphate to GCKR. The chromosomal proximity of the metabolically connected GCKR and KHK genes has a genetic linkage in type 2 diabetes. Fructosuria, or hepatic fructokinase deficiency, is a benign, asymptomatic defect of intermediary metabolism associated with heterozygosity for G50R and A43T mutations in KHK.Synonyms: EC=2.7.1.3, Hepatic fructokinase, KHK, Ketohexokinase
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基因ID
- 3795, 9606
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UniProt
- P50053
抗原
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