Aurora Kinase C 抗体 (N-Term)
Quick Overview for Aurora Kinase C 抗体 (N-Term) (ABIN359035)
抗原
See all Aurora Kinase C (AURKC) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody recognizes Aurora-C.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- KLH conjugated synthetic peptide selected from the N-terminal region of Human Aurora-C. Genename: AURKC
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亚型
- Ig Fraction
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunofluorescence: 1/100-1/500. Not Suitable for Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Aurora Kinase C (AURKC)
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别名
- Aurora Kinase C
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背景
- Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.Synonyms: AIE2, AIK3, AURKC, Aurora-C, Aurora/Ipl1-related kinase 3, Aurora/Ipl1/Eg2 protein 2, STK13, Serine/threonine-protein kinase 13
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分子量
- 35591 Da
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基因ID
- 6795, 9606
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UniProt
- Q9UQB9
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途径
- Cell Division Cycle, Maintenance of Protein Location
抗原
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