MTM1 抗体 (C-Term)
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北京 101111
Quick Overview for MTM1 抗体 (C-Term) (ABIN359029)
抗原
See all MTM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to MTM1.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MTM1.
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亚型
- Ig Fraction
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anti-Myotubularin 1 (MTM1) (AA 1-100) antibody
MTM1 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 1C10 unconjugated
anti-Myotubularin 1 (MTM1) (C-Term) antibodyVerified MTM1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Myotubularin 1 (MTM1) (AA 1-603) antibodyMTM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Myotubularin 1 (MTM1) (AA 225-275) antibodyMTM1 适用: 人, 小鼠, 大鼠 WB, FACS, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myotubularin 1 (MTM1) (AA 484-603) antibodyMTM1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myotubularin 1 (MTM1) (C-Term) antibodyMTM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myotubularin 1 (MTM1) (AA 1-603) antibodyMTM1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Myotubularin 1 (MTM1) (AA 1-30), (N-Term) antibodyMTM1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0722 unconjugated
anti-Myotubularin 1 (MTM1) (AA 566-594), (C-Term) antibodyMTM1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB0856 unconjugated
anti-Myotubularin 1 (MTM1) (AA 451-485) antibodyMTM1 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB52010 unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- MTM1 (Myotubularin 1 (MTM1))
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别名
- Myotubularin / MTM1
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背景
- MTM1 is a member of a protein family that encodes tyrosine phosphatases. Myotubularin is required for muscle cell differentiation and mutations in MTM1 have been identified as being responsible for X-linked myotubular myopathy. MTM1 is a potent phosphatidylinositol 3-phosphate phosphatase (PI(3)P). Mutations in the MTM1 gene that cause human myotubular myopathy dramatically reduce the ability of the phosphatase to dephosphorylate PI(3)P. The findings provided evidence that myotubularin exerts its effects during myogenesis by regulating the cellular levels of the inositol lipid PI(3)P.
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基因ID
- 4534, 9606
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UniProt
- Q13496
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途径
- Inositol Metabolic Process, Skeletal Muscle Fiber Development
抗原
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