PARP12 抗体 (C-Term)
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Quick Overview for PARP12 抗体 (C-Term) (ABIN358822)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to PARP12.
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纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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免疫原
- This PARP12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of mouse PARP12.
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亚型
- Ig Fraction
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anti-Poly (ADP-Ribose) Polymerase Family, Member 12 (PARP12) (AA 462-701) antibody
PARP12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 12 (PARP12) (C-Term) antibodyPARP12 适用: 人, 小鼠, 犬, Cow, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 12 (PARP12) (AA 454-483), (C-Term) antibodyPARP12 适用: 人 WB 宿主: 兔 Polyclonal RB14194 unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 12 (PARP12) (Middle Region) antibodyPARP12 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 12 (PARP12) antibodyPARP12 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- PARP12 (Poly (ADP-Ribose) Polymerase Family, Member 12 (PARP12))
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别名
- PARP12
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背景
- Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. Poly(ADP-ribose) polymerases (PARPs) now constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.Synonyms: PARP-12, Poly [ADP-ribose] polymerase 12, ZC3HDC1, Zinc finger CCCH domain-containing protein 1
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基因ID
- 243771, 10090
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UniProt
- Q8BZ20
抗原
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