HIRA 抗体 (Middle Region)
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- 抗原 See all HIRA 抗体
- HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HIRA antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to HIRA.
- 纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- 免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human HIRA.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product HIRA Primary Antibody
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anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 250-550) antibody
HIRA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5B6 unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 1-1017) antibodyHIRA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (pThr555) antibodyHIRA 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 1-200) antibodyHIRA 适用: Saccharomyces cerevisiae WB 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 251-350) antibodyHIRA 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 421-729) antibodyHIRA 适用: 人 WB 宿主: 小鼠 Monoclonal WC119-2H11 unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 421-729) antibodyHIRA 适用: 人, 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal WC119-2H11 unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 421-729) antibodyHIRA 适用: 人, 小鼠 WB, IP 宿主: 小鼠 Monoclonal WC15 unconjugated
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- 应用备注
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
- 别名
- HIRA / TUPLE1 (HIRA 产品)
- 别名
- HIRA antibody, wu:fb97b07 antibody, wu:fi43b08 antibody, si:ch211-188g24.3 antibody, AA138857 antibody, D16Ertd95e antibody, N28177 antibody, Tuple1 antibody, DGCR1 antibody, TUP1 antibody, TUPLE1 antibody, dgcr1 antibody, hira-A antibody, tup1 antibody, tuple1 antibody, homolog of histone chaperone HIRA antibody, histone cell cycle regulator antibody, histone cell cycle regulator a antibody, protein HIRA antibody, HIR histone cell cycle regulation defective homolog A (S. cerevisiae) antibody, HIRA antibody, histone cell cycle regulator S homeolog antibody, histone chaperone HIRA-like protein antibody, Tuple1/HirA antibody, HIRA antibody, hira antibody, LOC100052845 antibody, LOC100352472 antibody, LOC100407742 antibody, LOC100450459 antibody, LOC100467668 antibody, LOC100581135 antibody, LOC486424 antibody, Hira antibody, LOC732736 antibody, hira.S antibody
- 背景
- HIRA is a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this protein in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. It plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate protein in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.Synonyms: DGCR1, HIR, HIR histone cell cycle regulation defective homolog A, TUP1-like enhancer of split protein 1
- 基因ID
- 7290, 9606
- UniProt
- P54198
- 途径
- Chromatin Binding
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