HIRA 抗体 (Middle Region)
Quick Overview for HIRA 抗体 (Middle Region) (ABIN358780)
抗原
See all HIRA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- This antibody reacts to HIRA.
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纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human HIRA.
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亚型
- Ig Fraction
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anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 250-550) antibody
HIRA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5B6 unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 1-1017) antibodyHIRA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (pThr555) antibodyHIRA 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA 适用: 人 ICC, DB 宿主: 小鼠 Monoclonal 374C6a unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 251-350) antibodyHIRA 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) antibodyHIRA 适用: Saccharomyces cerevisiae WB 宿主: 小鼠 Monoclonal 4B9 unconjugated
anti-HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA) (AA 601-650) antibodyHIRA 适用: 人, 小鼠, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
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别名
- HIRA / TUPLE1
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背景
- HIRA is a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this protein in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. It plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate protein in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.Synonyms: DGCR1, HIR, HIR histone cell cycle regulation defective homolog A, TUP1-like enhancer of split protein 1
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基因ID
- 7290, 9606
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UniProt
- P54198
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途径
- Chromatin Binding
抗原
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