我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

Sclerostin 抗体 (N-Term)

Name: Sclerostin 抗体 (N-Term)
SKU: ABIN358751
Availability: OutOfStock

This anti-Sclerostin antibody is a 兔多克隆 antibody detecting Sclerostin in WB, IHC (p) 和 EIA. Suitable for 人和小鼠. This Primary Antibody has been cited in 1 publication.

Image no. 2 for anti-Sclerostin (SOST) (N-Term) antibody (ABIN358751) (Sclerostin 抗体 (N-Term))

Image no. 1 for anti-Sclerostin (SOST) (N-Term) antibody (ABIN358751) (Sclerostin 抗体 (N-Term))

2 images

(1 reference)

产品编号 ABIN358751

发货至: 中国

Quick Overview for Sclerostin 抗体 (N-Term) (ABIN358751)

抗原

See all Sclerostin (SOST) 抗体

Sclerostin (SOST)

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This Sclerostin antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Discover our top product SOST Primary Antibody

抗原表位
15

9

8

7

4

3

2

2

2

2

1

1

1

1

1

1

1
N-Term

特异性

This antibody reacts to SOST.

纯化方法

Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

免疫原

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SOST.

亚型

Ig Fraction
anti-Sclerostin (SOST) (AA 12-42), (N-Term) antibody
SOST 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB12388 unconjugated

anti-Sclerostin (SOST) (AA 25-213) antibody
SOST 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Sclerostin (SOST) (AA 24-213) antibody
SOST 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Sclerostin (SOST) (AA 24-213) antibody
SOST 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Sclerostin (SOST) (AA 121-180) antibody
SOST 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, ICC, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Sclerostin (SOST) (AA 25-209) antibody
SOST 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Sclerostin (SOST) (C-Term) antibody
Verified SOST 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Sclerostin (SOST) (AA 38-87) antibody
SOST 适用: 人, 犬, Pig, 马, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Sclerostin (SOST) (AA 134-163) antibody
SOST 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB13011 unconjugated

anti-Sclerostin (SOST) (AA 38-66), (N-Term) antibody
SOST 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB36187 unconjugated

应用备注

ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
状态

Liquid

浓度

0.25 mg/mL

缓冲液

PBS with 0.09 % (W/V) sodium azide

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Sato, Cregor, Delgado-Calle, Condon, Allen, Peacock, Plotkin, Bellido: "Protection From Glucocorticoid-Induced Osteoporosis by Anti-Catabolic Signaling in the Absence of Sost/Sclerostin." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 31, Issue 10, pp. 1791-1802, (2016) (PubMed).
抗原

Sclerostin (SOST)

别名

Sclerostin / SOST

背景

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.

基因ID

50964, 9606

UniProt

Q9BQB4