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MMP24 抗体 (Middle Region)

The 兔 多克隆 anti-MMP24 antibody is suitable to detect MMP24 in samples from 人. It has been validated for WB, IHC (p) 和 EIA.
产品编号 ABIN358694
发货至: 中国
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Quick Overview for MMP24 抗体 (Middle Region) (ABIN358694)

抗原

See all MMP24 抗体
MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))

适用

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宿主

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克隆类型

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多克隆

标记

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This MMP24 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    Middle Region

    特异性

    This antibody reacts top MMP24.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human MMP24.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Immunohistochemistry: 1/50 - 1/100. Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))

    别名

    MMP-24

    背景

    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP24 is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed matrix metalloproteinase 24 (MMP24).Synonyms: MMP24, MT-MMP 5, MT5-MMP, MT5MMP, Matrix metalloproteinase-24, Membrane-type matrix metalloproteinase 5

    基因ID

    10893, 5874

    UniProt

    Q9Y5R2
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