CRY1 抗体 (C-Term)
Quick Overview for CRY1 抗体 (C-Term) (ABIN358613)
抗原
See all CRY1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to CRY1.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide C-terminal region of human Cry1.
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亚型
- Ig Fraction
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anti-Cryptochrome 1 (Photolyase-Like) (CRY1) (AA 1-586) antibody
CRY1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4H4-1C4 unconjugated
anti-Cryptochrome 1 (Photolyase-Like) (CRY1) (AA 3-132) antibodyCRY1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cryptochrome 1 (Photolyase-Like) (CRY1) antibodyCRY1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 小鸡 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cryptochrome 1 (Photolyase-Like) (CRY1) (AA 507-586) antibodyCRY1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cryptochrome 1 (Photolyase-Like) (CRY1) (AA 1-587) antibodyCRY1 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4H4-1C4 unconjugated
anti-Cryptochrome 1 (Photolyase-Like) (CRY1) (AA 1-586) antibodyCRY1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cryptochrome 1 (Photolyase-Like) (CRY1) (AA 1-255) antibodyCRY1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cryptochrome 1 (Photolyase-Like) (CRY1) (AA 556-586), (C-Term) antibodyCRY1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1844 unconjugated
anti-Cryptochrome 1 (Photolyase-Like) (CRY1) antibodyCRY1 适用: 人 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 4H4-1C4 unconjugated
anti-Cryptochrome 1 (Photolyase-Like) (CRY1) (AA 151-200) antibodyCRY1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 豚鼠, 马, 绵羊, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))
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别名
- Cryptochrome-1
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背景
- Various biochemical, physiological and behavioural processes display circadian rhythms controlled by an internal biological clock. The central gears driving this clock appear to be composed of an autoregulatory transcription/posttranslation-based feedback loop. Cryptochrome 1 (CRY1) and 2 (CRY2) are DNA-binding flavoproteins that bear some homology to blue-light receptors and photolyases. In Drosophila, CRY is a photoreceptor for the circadian clock where it binds to the clock component TIM in a light-dependent fashion and blocks its function. Mammalian CRY1 and CRY2 function via light-independent interactions with circadian genes CLOCK and BMAL1, as well as with PER1, PER2, and TIM. They seem to act as light-independent components of the circadian clock and likely regulate Per1 transcriptional cycling via interactions with both the activator and its feedback inhibitors. Mutant mice not expressing the Cry1 or Cry2 protein display accelerated and delayed periodicity of locomotor activity, respectively. It appears that the combination of both proteins working together is essential to synchronize the organism to circadian phases. A critical balance between Cry1 and Cry2 is required for proper clock function, in complete darkness, double-mutant mice present with instantaneous arrhythmicity, indicating the absence of an internal circadian clock.Synonyms: CRY1, PHLL1
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基因ID
- 1407, 9606
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UniProt
- Q16526
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途径
- Response to Water Deprivation, Proton Transport
抗原
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