IRS2 抗体 (pTyr978)
Our Local Distributor
北京 101111
Quick Overview for IRS2 抗体 (pTyr978) (ABIN358522)
抗原
See all IRS2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pTyr978
-
特异性
- This antibody detects IRS2 pTyr978.
-
纯化方法
- Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
-
免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y978 of human IRS2.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
-
ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.25 mg/mL
-
缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
-
-
- IRS2 (Insulin Receptor Substrate 2 (IRS2))
-
别名
- IRS2
-
背景
- Insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. This protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.Synonyms: IRS-2, Insulin receptor substrate 2
-
分子量
- 137204 Da
-
基因ID
- 8660, 9606
-
UniProt
- Q9Y4H2
-
途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
抗原
-