TNK2 抗体 (pTyr518)
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北京 101111
Quick Overview for TNK2 抗体 (pTyr518) (ABIN358513)
抗原
See all TNK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr518
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特异性
- This antibody detects TNK2 / ACK1 pTyr518.
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纯化方法
- Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y518 of human ACK1.
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亚型
- Ig Fraction
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应用备注
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ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))
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别名
- TNK2 / ACK1
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背景
- ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.Synonyms: Activated CDC42 kinase 1
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分子量
- 114327 Da
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基因ID
- 10188, 9606
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UniProt
- Q07912
抗原
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