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TNK2 抗体 (pTyr518)

This anti-TNK2 antibody is a 兔 多克隆 antibody detecting TNK2 in EIA. Suitable for 人.
产品编号 ABIN358513
发货至: 中国
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Quick Overview for TNK2 抗体 (pTyr518) (ABIN358513)

抗原

See all TNK2 抗体
TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

适用

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宿主

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克隆类型

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多克隆

标记

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This TNK2 antibody is un-conjugated

应用范围

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Enzyme Immunoassay (EIA)
  • 抗原表位

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    pTyr518

    特异性

    This antibody detects TNK2 / ACK1 pTyr518.

    纯化方法

    Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y518 of human ACK1.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Dot Blot: 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

    别名

    TNK2 / ACK1

    背景

    ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.Synonyms: Activated CDC42 kinase 1

    分子量

    114327 Da

    基因ID

    10188, 9606

    UniProt

    Q07912
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