ANTXR1 抗体 (pTyr382)
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北京 101111
Quick Overview for ANTXR1 抗体 (pTyr382) (ABIN358475)
抗原
See all ANTXR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr382
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特异性
- This antibody detects Anthrax Toxin Receptor 1 (ANTXR1) pTyr382. Predicted to cross react with Mouse (100 % Antigen Homology).
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纯化方法
- Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y382 of human ANTXR1.
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亚型
- Ig Fraction
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应用备注
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ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
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别名
- Anthrax Toxin Receptor 1
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背景
- ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.Synonyms: ANTXR1, ATR, TEM8, Tumor endothelial marker 8
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分子量
- 62789 Da
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基因ID
- 84168, 9606
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UniProt
- Q9H6X2
抗原
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