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ANTXR1 抗体 (pTyr382)

This anti-ANTXR1 antibody is a 兔 多克隆 antibody detecting ANTXR1 in EIA. Suitable for 人.
产品编号 ABIN358475
发货至: 中国

Quick Overview for ANTXR1 抗体 (pTyr382) (ABIN358475)

抗原

See all ANTXR1 抗体
ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ANTXR1 antibody is un-conjugated

应用范围

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Enzyme Immunoassay (EIA)
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    pTyr382

    特异性

    This antibody detects Anthrax Toxin Receptor 1 (ANTXR1) pTyr382. Predicted to cross react with Mouse (100 % Antigen Homology).

    纯化方法

    Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y382 of human ANTXR1.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Dot Blot: 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

    别名

    Anthrax Toxin Receptor 1

    背景

    ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.Synonyms: ANTXR1, ATR, TEM8, Tumor endothelial marker 8

    分子量

    62789 Da

    基因ID

    84168, 9606

    UniProt

    Q9H6X2
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