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INPP5D 抗体 (Middle Region)

This anti-INPP5D antibody is a 兔 多克隆 antibody detecting INPP5D in WB 和 EIA. Suitable for 人.
产品编号 ABIN358021
发货至: 中国

Quick Overview for INPP5D 抗体 (Middle Region) (ABIN358021)

抗原

See all INPP5D 抗体
INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))

适用

  • 90
  • 63
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  • 3
  • 2
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  • 1
  • 1

宿主

  • 88
  • 3

克隆类型

  • 70
  • 21
多克隆

标记

  • 34
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  • 2
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  • 2
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  • 2
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  • 2
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  • 1
This INPP5D antibody is un-conjugated

应用范围

  • 61
  • 22
  • 17
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 19
    • 18
    • 7
    • 3
    • 3
    • 1
    • 1
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    • 1
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    • 1
    • 1
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    • 1
    Middle Region

    特异性

    This antibody detects INPP5D (Center).

    纯化方法

    Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human INPP5D.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western Blot: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))

    别名

    INPP5D

    背景

    INPP5D is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and it is a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival.Synonyms: 4, 5-trisphosphate 5-phosphatase 1, Inositol polyphosphate-5-phosphatase of 145 kDa, Phosphatidylinositol-3, SH2 domain-containing inositol-5'-phosphatase 1, SHIP, SHIP-1, SHIP1, SIP-145, p150Ship

    分子量

    133292 Da

    基因ID

    3635, 9606

    UniProt

    Q92835

    途径

    TCR Signaling, BCR Signaling, Warburg Effect
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